Mix all of the ingredients for the pot roast seasoning in a small bowl. Remove the chuck roast from the packaging and sprinkle the seasoning over the pot roast. Massage the seasoning into the roast with your hands. Be sure the whole roast is coated. Let the roast sit in the seasoning for at least 30 minutes.
Preheat the oven to 300ºF.
Heat a large Dutch oven with a lid over medium/high heat. Add the olive oil to the Dutch oven. When the olive oil is fragrant, add the roast and sear it for 3-4 minutes on each side until golden brown. Remove the roast from the Dutch oven.
Deglaze the Dutch oven with the red wine and scrape the brown bits from the bottom with a spatula. Add the onion to the wine and season with salt. Let the onion saute for 2-3 minutes. Then, add the garlic, and cook for another 1 minute.
Add the carrots, celery, and potatoes to the Dutch oven and stir all the ingredients together. Let the vegetables cook for 4-5 minutes.
Whisk together the beef broth, mustard, and Worcestershire sauce in a separate bowl and then pour the liquid over the vegetables. Place the fresh herbs and roast on top of the vegetables.
Cover the Dutch oven and bake for 3-4 hours or until the roast falls apart with a fork. Flip the roast after 2 hours so each side can roast in the cooking liquid. Continue to cook until your pot roast is fall-off-the-bone tender. Time will vary depending on the size of your roast and your oven.
Remove the roast from the oven and let it rest for 10 minutes. Enjoy immediately after discarding the herb stems.
Remove the roast and vegetables from the Dutch oven and set aside. Discard the herb stems and add 2-3 teaspoons of cornstarch to the pot. Whisk the cornstarch into the cooking liquid. If the liquid is still hot, the cooking liquid should thicken within a few minutes. If the cooking liquid is not hot, bring the liquid to a boil over high heat on the stovetop and then add the cornstarch.
Add the roast and vegetables back into the pot with the gravy and enjoy.